Matrixyl 200mg (Topical)

Matrixyl (Palmitoyl Pentapeptide-4) is an advanced synthetic lipopentapeptide available at The Peptide Store in a high-concentration 200mg topical lyophilized format, verified at ≥98% purity for professional biochemical research applications. Engineered as a specialized laboratory tool for investigating fibroblast activation, extracellular matrix (ECM) structural repair, and connective tissue regeneration pathways, this compound offers researchers a rigorously characterized baseline matrix for high-resolution dermal tissue studies. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Matrixyl, biochemically classified as Palmitoyl Pentapeptide-4 (formerly designated Palmitoyl Pentapeptide-3), is a highly specialized lipopentapeptide synthesized for advanced studies in cutaneous tissue remodeling, ECM structural preservation, and cellular signaling cascades. The Peptide Store supplies this targeted dermal modulator in a stable, ultra-pure topical lyophilized format, making it an ideal research-grade compound for biochemistry, dermatology, and regenerative medicine laboratories seeking to examine structural protein synthesis and lipid-conjugated peptide behavior in controlled experimental settings.

Peptide Structure & Amino Acid Sequence

Matrixyl is composed of a core five-amino-acid sequence covalently linked to a palmitoyl fatty acid chain. The primary sequence is expressed as Pal-Lys-Thr-Thr-Lys-Ser, forming a lipid-conjugated messenger peptide architecture. This palmitoylation modification significantly enhances the molecule’s affinity for phospholipid bilayers, facilitating deeper penetration into dermal tissue matrices during topical application in controlled research environments. The pentapeptide backbone mimics a fragment of type I procollagen, positioning Matrixyl as a structurally relevant tool for ECM signaling pathway investigations.

Chemical & Physical Characteristics

• Common Name: Matrixyl
• IUPAC Classification: Palmitoyl Pentapeptide-4
• Sequence: Pal-Lys-Thr-Thr-Lys-Ser
• Peptide Type: Lipopentapeptide (palmitoylated)
• Molecular Formula: C₃₉H₇₅N₇O₁₀
• Molecular Weight: Approximately 802.05 g/mol
• Physical State: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers with mild cosolvents; suitable for topical formulation vehicles in research settings
• Application Format: Topical research use

Purity & Analytical Verification (HPLC & MS)

Every batch of Matrixyl 200mg supplied by The Peptide Store undergoes rigorous analytical verification to confirm compound identity and purity. High-performance liquid chromatography (HPLC) analysis is employed to quantify purity levels, consistently achieving a verified result of ≥98%. Mass spectrometry (MS) is additionally applied to confirm molecular weight accuracy and structural integrity, ensuring that each unit dispatched meets the exacting standards required for reproducible laboratory research outcomes. Certificates of Analysis (CoA) are available upon request for full traceability.

Quality Control & Lyophilization Integrity

Matrixyl is produced through established solid-phase peptide synthesis (SPPS) protocols, followed by palmitoyl conjugation under controlled conditions. The lyophilization process removes residual moisture to a level consistent with long-term compound stability, preserving the structural and biochemical integrity of the peptide across extended storage periods. Each batch is subject to multi-point quality control inspection prior to release, encompassing identity confirmation, purity threshold verification, and physical appearance assessment to ensure consistent, research-grade quality.

Safety, Handling & Laboratory Precautions

As with all research-grade biochemical compounds, appropriate laboratory safety protocols must be observed when handling Matrixyl. Researchers should wear suitable personal protective equipment (PPE), including laboratory gloves, protective eyewear, and appropriate lab attire. This compound is intended exclusively for use by qualified scientific personnel in properly equipped research facilities. Avoid inhalation of lyophilized powder. Store away from incompatible materials and keep out of reach of unauthorized individuals. All handling must comply with applicable institutional biosafety guidelines.

Reconstitution, Packaging & Storage

Matrixyl is supplied in lyophilized powder form, packaged under inert conditions to maintain compound integrity during transit and storage. For topical research formulation, researchers should consult peer-reviewed literature and established laboratory protocols to determine appropriate vehicle systems and concentrations relevant to their specific experimental design. Upon receipt, store the lyophilized product at -20°C in a dry, dark environment. Once reconstituted for research purposes, use promptly and avoid repeated freeze-thaw cycles to preserve compound stability.

Intended Research Use & Market Positioning

Matrixyl 200mg (Topical) is positioned as a premium research tool for academic institutions, independent research organizations, and private laboratories focused on dermal biology, ECM dynamics, and lipopeptide pharmacology. Its structural similarity to procollagen-derived sequences makes it a valuable reference compound in studies examining fibroblast behavior, collagen synthesis pathways, and matrix metalloproteinase (MMP) regulation in vitro. The Peptide Store offers this compound at a competitive best price, reflecting our commitment to supplying high-quality, affordable research peptides to the global scientific community.

Ordering, Availability & Fulfillment

Researchers can conveniently buy Matrixyl 200mg online through The Peptide Store with confidence in product authenticity, purity documentation, and efficient order fulfillment. We maintain consistent stock availability to support ongoing research programs, with secure checkout, fast dispatch, and discreet laboratory-standard packaging. Order now to take advantage of our competitive pricing structure and reliable supply chain. Our customer support team is available to assist with product inquiries, CoA requests, and bulk ordering arrangements.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Matrixyl 200mg (Topical) is sold exclusively as a laboratory research reagent. The Peptide Store makes no representations regarding the suitability of this compound for any application beyond controlled scientific investigation. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the acquisition, possession, and use of research peptides. This product has not been evaluated by any regulatory authority for safety or efficacy in humans or animals.