N-Acetyl Semax Amidate 30mg

N-Acetyl Semax Amidate is an advanced synthetic neuroactive peptide analog derived from the ACTH(4–10) core fragment, featuring dual terminal modifications for enhanced structural stability. Available from The Peptide Store at ≥98% purity, this 30mg lyophilized formulation is designed exclusively for qualified laboratory and neuroscience research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

N-Acetyl Semax Amidate represents one of the most structurally sophisticated derivatives within the Semax peptide family. Built upon the endogenous adrenocorticotropic hormone fragment ACTH(4–10), this analog has been engineered with a dual-modification strategy — N-terminal acetylation and C-terminal amidation — to produce a compound with markedly improved enzymatic resistance and membrane permeability. The Peptide Store supplies this compound as a precision-weighed 30mg lyophilized cake, making it an ideal high-purity reagent for neurobiology, neurotrophic signaling, and synaptic plasticity research programs requiring consistent, multi-dose experimental frameworks.

Peptide Structure & Amino Acid Sequence

The base sequence of N-Acetyl Semax Amidate follows the heptapeptide core: Met-Glu-His-Phe-Pro-Gly-Pro, which mirrors the biologically active fragment of ACTH(4–10). This sequence is further modified at both termini: an acetyl group (CH₃CO–) is appended to the N-terminus, and an amide group (–NH₂) replaces the free carboxyl at the C-terminus. These dual structural alterations collectively increase lipophilicity, confer resistance to plasma peptidase degradation, and enhance overall molecular stability — properties that make this compound particularly valuable for controlled in vitro and ex vivo research environments.

Chemical & Physical Characteristics

• Peptide Class: Synthetic ACTH(4–10) analog
• Modifications: N-terminal acetylation; C-terminal amidation
• Molecular Formula: C₃₈H₅₄N₁₀O₁₀S (approximate, subject to batch verification)
• Physical Form: Lyophilized white to off-white cake or powder
• Solubility: Soluble in aqueous buffers and select organic solvents under laboratory conditions
• Stability: Enhanced enzymatic resistance due to dual terminal protection
• Lipophilicity: Elevated relative to unmodified Semax, supporting blood-brain barrier permeability modeling

Purity & Analytical Verification (HPLC & MS)

Every batch of N-Acetyl Semax Amidate supplied by The Peptide Store is independently verified to a minimum purity of ≥98% using reverse-phase high-performance liquid chromatography (RP-HPLC). Complementary mass spectrometry (MS) analysis confirms molecular identity and rules out truncated sequences, deletion products, or oxidative impurities. Analytical certificates are available upon request, providing researchers with full traceability and confidence in the integrity of their experimental data. This rigorous dual-method verification is a cornerstone of our quality assurance process.

Quality Control & Lyophilization Integrity

N-Acetyl Semax Amidate is produced under strict quality control protocols and lyophilized using validated freeze-drying cycles to ensure uniform cake morphology, minimal residual moisture, and optimal long-term stability. Each 30mg unit is sealed under inert atmosphere conditions to prevent oxidative degradation during storage and transit. The lyophilized format also provides researchers with the flexibility to reconstitute precise working concentrations as required by their specific assay design, without compromising peptide integrity.

Safety, Handling & Laboratory Precautions

This compound is intended exclusively for use by trained laboratory professionals in properly equipped research facilities. Standard laboratory personal protective equipment (PPE) — including nitrile gloves, safety goggles, and a laboratory coat — should be worn at all times when handling this material. Researchers should consult the relevant Safety Data Sheet (SDS) before use. This product is not approved for administration to humans or animals, and must not be used in any clinical, therapeutic, diagnostic, or food-related context. All waste disposal must comply with applicable institutional and governmental regulations.

Reconstitution, Packaging & Storage

N-Acetyl Semax Amidate is packaged as a lyophilized solid in a sealed, laboratory-grade vial. For reconstitution guidance, researchers should refer to validated laboratory protocols appropriate to their specific experimental conditions. As a general principle, sterile aqueous buffers are commonly used for peptide reconstitution in research settings. Once reconstituted, working solutions should be aliquoted and stored appropriately to minimize freeze-thaw degradation. The lyophilized product should be stored at –20°C or below, away from light and moisture, to preserve maximum stability and shelf life.

Intended Research Use & Market Positioning

N-Acetyl Semax Amidate is positioned as a premier research tool for neuroscience laboratories investigating neurotrophic factor signaling, BDNF expression modulation, synaptic plasticity mechanisms, and blood-brain barrier permeability modeling. Its dual-modified architecture makes it especially suitable for studies requiring prolonged peptide stability in biological matrices. The Peptide Store offers this compound at a competitive best price, making it accessible to academic institutions, contract research organizations, and independent research groups seeking reliable, high-purity reagents.

Ordering, Availability & Fulfillment

The Peptide Store makes it straightforward to buy N-Acetyl Semax Amidate online with confidence. Our ordering process is streamlined for both individual researchers and institutional procurement teams. All orders are fulfilled promptly from our quality-verified inventory, with discreet, secure packaging to ensure product integrity upon arrival. Whether you are looking to order now for an active study or sourcing for a future research program, The Peptide Store offers reliable availability, transparent pricing, and responsive customer support.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. N-Acetyl Semax Amidate is sold exclusively as a laboratory research reagent. It has not been evaluated or approved by any regulatory authority for therapeutic, prophylactic, or diagnostic use in humans or animals. Purchasers are solely responsible for ensuring that acquisition, possession, and use of this compound comply with all applicable local, national, and international laws and institutional regulations. The Peptide Store assumes no liability for misuse or unauthorized application of this product.