Thymosin Alpha-1 3mg

Thymosin Alpha-1 3mg is a highly purified, analytically verified synthetic analog of the endogenous thymic peptide naturally derived from prothymosin alpha, offered by The Peptide Store at ≥98% purity. This 28-amino acid acetylated compound is one of the most extensively studied peptides in modern immunological science, providing researchers with a well-characterized tool for investigating T-cell maturation, innate immune signaling, and thymic biology. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

First isolated from thymosin fraction 5 by Dr. Allan Goldstein and colleagues in the 1970s, Thymosin Alpha-1 has since accumulated one of the most robust bodies of preclinical literature of any synthetic thymic analog. At The Peptide Store, this compound is available for qualified laboratory researchers seeking a reliable, high-purity reference peptide for immunological investigation. Its consistent performance across peer-reviewed studies makes it an indispensable tool for investigators engaged in immune modulation, T-cell biology, and innate defense pathway research.

Peptide Structure & Amino Acid Sequence

Thymosin Alpha-1 is a 28-amino acid acetylated peptide with the sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH. The N-terminal acetylation is a defining structural feature that distinguishes it from its precursor prothymosin alpha and contributes to its biological stability in research settings. Its molecular weight is approximately 3,108 Da, and it carries the CAS number 62304-98-7. This precise sequence has been replicated synthetically to mirror the endogenous human thymic peptide with exceptional fidelity.

Chemical & Physical Characteristics

• Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅
• Molecular Weight: ~3,108 Da
• CAS Number: 62304-98-7
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers; typical research-grade reconstitution solvents apply
• Storage Stability: Stable under recommended cold-chain conditions

These characteristics make Thymosin Alpha-1 a chemically tractable compound for a range of in vitro and ex vivo research protocols within properly equipped laboratory environments.

Purity & Analytical Verification (HPLC & MS)

Every batch of Thymosin Alpha-1 3mg supplied by The Peptide Store undergoes rigorous analytical verification prior to release. Purity is confirmed at ≥98% using reverse-phase high-performance liquid chromatography (RP-HPLC), with mass spectrometry (MS) employed to confirm molecular identity and sequence integrity. Certificates of Analysis (CoA) are available upon request and accompany each order, providing full traceability and confidence for research documentation and publication-grade experimental design.

Quality Control & Lyophilization Integrity

Thymosin Alpha-1 is produced under stringent quality control conditions using solid-phase peptide synthesis (SPPS) methodologies. Following synthesis and purification, the peptide is lyophilized — a freeze-drying process that removes residual moisture and maximizes long-term stability. Lyophilization integrity is assessed to ensure a consistent, homogenous powder free from particulate contamination. Each unit is independently tested to meet The Peptide Store’s quality benchmarks before being released for sale.

Safety, Handling & Laboratory Precautions

Thymosin Alpha-1 3mg is intended exclusively for use by trained laboratory professionals in appropriately equipped research facilities. Standard laboratory safety practices should be observed at all times, including the use of appropriate personal protective equipment (PPE). This compound should not be handled outside of a controlled laboratory environment. Researchers are advised to consult applicable institutional safety protocols and relevant regulatory guidelines before initiating any experimental work involving this peptide.

Reconstitution, Packaging & Storage

Thymosin Alpha-1 3mg is supplied as a lyophilized powder in a sealed vial suitable for research laboratory use. For optimal stability, the lyophilized product should be stored at −20°C, protected from light and moisture. Once reconstituted using an appropriate research-grade solvent in accordance with your institutional protocols, the resulting solution should be aliquoted and stored under cold conditions to minimize degradation. Reconstitution methods and solvent selection should be determined by qualified researchers based on experimental requirements. This product is not supplied with instructions for injection or any consumptive use.

Intended Research Use & Market Positioning

Thymosin Alpha-1 3mg is positioned as a premium immunological research peptide for academic institutions, contract research organizations (CROs), and independent investigators studying thymic biology, T-cell differentiation, toll-like receptor (TLR) signaling, and innate immune defense pathways. Its well-documented preclinical profile and structural authenticity make it a preferred reference compound in studies exploring immunomodulatory mechanisms at the cellular and molecular level. The Peptide Store offers this compound as part of a curated catalog of high-purity research peptides available to buy online with confidence.

Ordering, Availability & Fulfillment

Thymosin Alpha-1 3mg is available for sale now at The Peptide Store. Order online through our secure eCommerce platform with fast processing and reliable fulfillment. We are committed to providing researchers with the best price on verified, high-purity peptides without compromising on analytical standards. All orders are dispatched with CoA documentation, and our team is available to assist with any product or order inquiries. Buy Thymosin Alpha-1 online today and experience the quality and consistency that research professionals trust.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Thymosin Alpha-1 3mg is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding the therapeutic, prophylactic, or diagnostic utility of this compound. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international laws and regulations governing the purchase, possession, and use of research peptides. This product must not be administered to humans or animals under any circumstances.