Follistatin 344 1mg

Follistatin 344 is a premium synthetic glycoprotein analogue manufactured to ≥98% purity, engineered as a precise biochemical tool for advanced musculoskeletal development, cellular proliferation, and tissue growth research. Available as a lyophilized vial from The Peptide Store, this compound supports rigorous investigation into myostatin blockade, activin neutralization, and muscle hypertrophy signaling pathways. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Follistatin 344 is biochemically classified as a full-length autocrine glycoprotein analogue and is one of the most studied regulatory proteins in musculoskeletal and metabolic research. As a potent non-competitive antagonist of TGF-β superfamily ligands, it is widely employed in laboratory settings to explore the molecular mechanisms governing tissue growth, cellular longevity, and systemic metabolic regulation. The Peptide Store supplies Follistatin 344 as a high-integrity lyophilized research reagent, suitable for biochemistry, cell biology, and molecular pharmacology applications.

Peptide Structure & Amino Acid Sequence

Follistatin 344 derives its name from its 344 amino acid sequence, distinguishing it from the shorter Follistatin 288 isoform. The 344 isoform retains a C-terminal extension that enhances its circulating half-life and binding affinity relative to truncated variants. Its structure features three cysteine-rich follistatin domains (FSD1, FSD2, FSD3) flanked by an N-terminal domain responsible for high-affinity ligand binding. This architecture enables selective and high-potency neutralization of activin A, activin B, myostatin (GDF-8), and several bone morphogenetic proteins (BMPs), making it a uniquely versatile molecular probe in growth factor biology research.

Chemical & Physical Characteristics

• Molecular Formula: Complex glycoprotein; sequence-derived MW approximately 35–40 kDa (glycosylated form)
• Amino Acid Length: 344 residues
• Form: Lyophilized white to off-white powder
• Solubility: Soluble in aqueous buffers under standard laboratory conditions
• CAS Classification: Recombinant/synthetic glycoprotein analogue
• Storage Temperature: −20°C (long-term); 2–8°C (short-term post-reconstitution)

Purity & Analytical Verification (HPLC & MS)

Every batch of Follistatin 344 offered by The Peptide Store undergoes rigorous analytical verification to confirm ≥98% purity. High-performance liquid chromatography (HPLC) is employed to assess compound homogeneity and identify any trace impurities, while mass spectrometry (MS) confirms molecular weight integrity and sequence fidelity. These dual-validation protocols ensure that each vial meets the exacting standards required for reproducible, publication-quality research outcomes. Certificates of Analysis (CoA) reflecting these analytical results are available upon request.

Quality Control & Lyophilization Integrity

Follistatin 344 is processed using pharmaceutical-grade lyophilization technology, which removes moisture under controlled vacuum and temperature conditions to preserve structural integrity and bioactivity over extended storage periods. The lyophilization process minimizes degradation risks associated with liquid-phase storage, ensuring that researchers receive a stable, intact compound ready for reconstitution in a controlled laboratory environment. Each vial is sealed under inert gas and inspected for visual and physical integrity prior to dispatch from The Peptide Store.

Safety, Handling & Laboratory Precautions

Follistatin 344 is intended exclusively for in vitro and preclinical laboratory research. Researchers working with this compound should observe standard laboratory safety protocols, including the use of appropriate personal protective equipment (PPE) such as gloves, lab coats, and eye protection. This peptide should be handled in a clean, controlled environment to prevent contamination. Avoid exposure to repeated freeze-thaw cycles, direct UV light, and elevated temperatures, all of which may compromise structural and functional integrity.

Reconstitution, Packaging & Storage

Follistatin 344 is supplied as a lyophilized powder in a sealed, sterile vial. For laboratory reconstitution, researchers should consult peer-reviewed protocols appropriate to their specific assay requirements, using sterile aqueous buffers or carrier solutions as dictated by experimental design. Once reconstituted, aliquot immediately to minimize freeze-thaw degradation. Store the lyophilized vial at −20°C for long-term preservation. Reconstituted solutions should be stored at 2–8°C and used within a timeframe consistent with validated laboratory protocols. Packaging is designed to maintain cold-chain integrity during transit.

Intended Research Use & Market Positioning

Follistatin 344 is positioned as a premier research reagent for scientists investigating myostatin inhibition, activin signaling, skeletal muscle hypertrophy pathways, and age-associated tissue decline. It is widely utilized in academic, biotechnology, and pharmaceutical research settings as a high-fidelity molecular tool. The Peptide Store offers Follistatin 344 for sale at a competitive best price, making this advanced glycoprotein analogue accessible to research institutions and independent laboratories worldwide seeking to buy online with confidence.

Ordering, Availability & Fulfillment

The Peptide Store maintains consistent stock availability of Follistatin 344, enabling researchers to order now without delays. Our streamlined checkout process, secure payment infrastructure, and reliable cold-chain logistics ensure that every order is fulfilled with precision and speed. Whether you are restocking an ongoing study or initiating a new research program, our team is committed to providing a seamless purchasing experience. Contact our support team for bulk pricing inquiries or custom fulfillment arrangements.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Follistatin 344 is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding therapeutic efficacy, safety for biological administration, or suitability for any application outside of controlled in vitro or preclinical research environments. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the acquisition, handling, and use of research peptides and biochemical reagents. By placing an order, the buyer confirms that this product will be used strictly within a regulated research context.