hGH Fragment 176-191 6mg

hGH Fragment 176–191 is a premium-grade, ≥98% purity synthetic peptide comprising a 15-amino-acid sequence that precisely mirrors the C-terminal domain of full-length human growth hormone. Available from The Peptide Store as a rigorously quality-controlled lyophilized research compound, this isolated biochemical tool is designed exclusively for scientific investigation of adipocyte lipolysis and lipid oxidation pathways — without inducing somatotropic growth effects or elevating systemic IGF-1 profiles. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

hGH Fragment 176–191 has emerged as one of the most studied C-terminal growth hormone-derived peptides in modern metabolic research. By isolating the specific domain of human growth hormone responsible for adipose tissue modification, researchers gain a uniquely targeted biochemical probe that decouples fat metabolism signaling from the anabolic, proliferative, and IGF-1-mediated pathways associated with the full-length hormone. This makes it an exceptionally valuable tool for laboratories investigating energy homeostasis, endocrine signaling cascades, and lipid oxidation mechanisms at a molecular level. The Peptide Store supplies this compound to qualified research institutions and independent investigators seeking a stable, reproducible, ultra-pure baseline for non-diabetogenic lipolytic studies.

Peptide Structure & Amino Acid Sequence

hGH Fragment 176–191 is defined by a 15-amino-acid linear sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly. This sequence corresponds directly to residues 176 through 191 of the native human growth hormone polypeptide chain. The N-terminal residues governing skeletal growth, cellular proliferation, and IGF-1 transcription are entirely absent from this fragment, conferring a highly selective biochemical profile. The two cysteine residues within the chain introduce structural constraints that contribute to the peptide’s conformational stability and receptor interaction specificity, making it a precise instrument for mechanistic research.

Chemical & Physical Characteristics

• Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
• Molecular Weight: Approximately 1817.1 Da
• Sequence Length: 15 amino acids
• CAS Number: 221231-10-3
• Appearance: White to off-white lyophilized powder or cake
• Solubility: Soluble in aqueous buffer systems at appropriate pH for in vitro laboratory use
• Storage Form: Lyophilized solid for enhanced long-term stability

Purity & Analytical Verification (HPLC & MS)

Every batch of hGH Fragment 176–191 supplied by The Peptide Store undergoes stringent analytical verification to confirm ≥98% purity. High-performance liquid chromatography (HPLC) is employed to resolve and quantify peptide content, ensuring that no significant impurity peaks compromise the compound’s integrity. Mass spectrometry (MS) analysis independently confirms the correct molecular weight and sequence identity of each production lot. Researchers can rely on these dual-method verification protocols to ensure experimental reproducibility and data integrity across all in vitro research applications.

Quality Control & Lyophilization Integrity

Lyophilization — or freeze-drying — is the preservation method of choice for sensitive peptide compounds such as hGH Fragment 176–191. This process removes residual moisture under vacuum conditions, yielding a stable, low-humidity solid that resists degradation during storage and transit. Each unit is inspected for lyophilization cake integrity, correct fill weight, and container seal quality before dispatch. Batch-specific certificates of analysis (CoA) are available upon request, providing full traceability from synthesis through quality release for every order fulfilled by The Peptide Store.

Safety, Handling & Laboratory Precautions

hGH Fragment 176–191 is intended solely for use by trained scientific personnel in properly equipped laboratory environments. Standard laboratory safety protocols should be observed at all times, including the use of appropriate personal protective equipment (PPE) such as gloves, lab coats, and eye protection. This compound must never be administered to humans or animals. It is not approved for clinical, therapeutic, or diagnostic use. Researchers should consult applicable institutional biosafety guidelines and local regulatory requirements before handling this or any synthetic peptide compound.

Reconstitution, Packaging & Storage

hGH Fragment 176–191 is supplied as a lyophilized solid in sealed, inert packaging designed to protect compound integrity during storage and shipment. For laboratory reconstitution, researchers should use sterile aqueous buffer systems appropriate to their specific experimental protocols. Reconstituted solutions should be prepared under aseptic conditions, aliquoted as needed, and stored according to established laboratory best practices for peptide solutions. The lyophilized form should be stored at −20°C or below, protected from light and moisture, to maintain maximum stability over the product’s shelf life.

Intended Research Use & Market Positioning

hGH Fragment 176–191 is positioned as a premium-grade research tool for pharmacology, biochemistry, and endocrinology laboratories investigating adipocyte biology, lipid metabolism, and non-diabetogenic lipolytic signaling. Its selective biochemical profile — absent of growth-promoting or IGF-1-elevating activity — makes it uniquely suited for mechanistic studies that require isolation of fat metabolism pathways from broader anabolic endocrine effects. Researchers seeking to buy hGH Fragment 176–191 online will find The Peptide Store’s offering competitively priced, analytically verified, and ready for immediate dispatch.

Ordering, Availability & Fulfillment

The Peptide Store offers hGH Fragment 176–191 for sale to qualified research buyers with fast, reliable order fulfillment. Orders are processed promptly, with secure packaging designed to preserve lyophilization integrity throughout transit. Our platform supports straightforward online ordering, and our team is available to assist with bulk inquiries, documentation requests, or certificate of analysis provision. Order now to secure your research supply at the best price available from a trusted peptide supplier committed to analytical excellence and compliance-first operations.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. hGH Fragment 176–191 is sold exclusively as a laboratory research reagent. It has not been evaluated or approved by any regulatory authority for use in humans or animals. The Peptide Store assumes no liability for misuse, improper handling, or application of this compound outside of its intended research context. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international laws and regulations governing the purchase, possession, and use of synthetic research peptides.