Humanin 10mg

Humanin 10mg is a premium-grade, synthetic 24-amino-acid mitochondrial-derived peptide (MDP) manufactured to ≥98% purity and supplied exclusively as a lyophilized research compound. This formulation serves as a highly specialized biochemical probe for investigating mitochondrial signaling cascades, Bax-mediated apoptosis suppression, and cellular cytoprotection pathways under induced oxidative stress. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Humanin is a biologically unique endogenous peptide encoded within the mitochondrial genome, specifically by the 16S ribosomal RNA gene (MT-RNR2). First identified through functional screening of a cDNA library derived from the surviving neurons of Alzheimer’s disease patients, Humanin has since become a foundational subject of inquiry across mitochondrial biology, metabolic regulation, neuroprotection, and cellular stress response research. The Peptide Store supplies this compound as a precisely formulated 10mg lyophilized cake, offering research laboratories a stable, ultra-pure baseline material for in vitro and biochemical investigations.

Peptide Structure & Amino Acid Sequence

Humanin is a linear 24-amino-acid peptide with the following confirmed sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala. This sequence is directly translated from the mitochondrial 16S rRNA open reading frame and is conserved across multiple mammalian species, underscoring its fundamental biological relevance. The peptide operates via both intracellular and extracellular receptor-mediated pathways, functioning as a global cytoprotective signaling molecule under conditions of physiological or environmentally induced cellular stress. Its structural integrity is maintained through lyophilization, ensuring sequence fidelity upon arrival at the research facility.

Chemical & Physical Characteristics

• Peptide Length: 24 amino acids
• Molecular Formula: C₁₁₂H₁₉₅N₃₃O₂₉S
• Molecular Weight: Approximately 2,887 Da
• Appearance: White to off-white lyophilized powder or cake
• Solubility: Soluble in aqueous buffers; solubility characteristics determined by end-user laboratory protocols
• Storage Form: Lyophilized solid for maximum stability during transit and storage

Purity & Analytical Verification (HPLC & MS)

Every batch of Humanin supplied by The Peptide Store undergoes rigorous analytical verification to confirm ≥98% purity. High-Performance Liquid Chromatography (HPLC) is employed to assess compound homogeneity and detect any residual impurities or synthesis byproducts. Mass Spectrometry (MS) is used to confirm the precise molecular mass and validate the correct amino acid sequence. These dual analytical methods together ensure that each unit delivered meets the highest standards expected by professional research environments. Certificates of Analysis (CoA) reflecting these results are available upon request.

Quality Control & Lyophilization Integrity

Humanin 10mg is produced under controlled synthesis conditions using solid-phase peptide synthesis (SPPS) methodologies. Following synthesis and purification, the peptide undergoes lyophilization — a freeze-drying process that removes residual moisture and converts the compound into a stable, shelf-stable solid cake. This process preserves structural integrity, prevents degradation, and ensures the compound remains analytically consistent from the point of manufacture through to laboratory receipt. Each vial is sealed under inert conditions to minimize oxidative exposure during storage and transit.

Safety, Handling & Laboratory Precautions

Humanin 10mg is intended exclusively for use by trained laboratory professionals in controlled research settings. Appropriate personal protective equipment (PPE) — including gloves, lab coat, and eye protection — should be worn when handling this compound. All handling, preparation, and disposal must comply with institutional biosafety protocols and applicable local regulations. This compound must not be ingested, injected, inhaled, or applied to any biological organism. It is strictly a research-grade reagent.

Reconstitution, Packaging & Storage

Upon receipt, Humanin 10mg should be stored at −20°C in a dry, dark environment to maintain long-term stability. Reconstitution procedures are the sole responsibility of the receiving researcher and must comply with validated in vitro laboratory protocols. No reconstitution guidance for injection, consumption, or in vivo use is provided or implied. The compound is packaged in a sealed, labeled research vial appropriate for laboratory handling and short-term bench use following reconstitution.

Intended Research Use & Market Positioning

Humanin 10mg is positioned as a premium research tool for scientists investigating mitochondrial-derived peptide biology, Bax-mediated apoptosis inhibition, neuroprotective signaling mechanisms, insulin sensitivity modulation, and age-related cellular stress pathways. It is widely referenced in peer-reviewed literature relating to neurodegeneration, metabolic disease, and cytoprotection research. The Peptide Store offers this compound at a competitive best price with reliable availability, making it an accessible choice for academic, biotech, and pharmaceutical research teams seeking to buy high-purity mitochondrial peptides online.

Ordering, Availability & Fulfillment

Humanin 10mg is available for sale now through The Peptide Store. Ordering is straightforward via our secure online platform, with options for domestic and international fulfillment. All orders are processed promptly, with discreet, compliant packaging and tracking provided upon dispatch. Research institutions, independent laboratories, and qualified procurement teams are encouraged to order now to secure current stock at the best available price. Bulk inquiry options may also be available — contact our team for details.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Humanin 10mg is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding therapeutic efficacy, safety for biological administration, or suitability for any use beyond controlled in vitro research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the acquisition, possession, and use of research peptides. This product must not be used in any manner inconsistent with its research-only designation.