N-Acetyl Epithalon Amidate 20mg

N-Acetyl Epithalon Amidate is a chemically stabilized, N-terminally acetylated and C-terminally amidated analog of the classic pineal tetrapeptide Epitalon, supplied at ≥98% purity and verified by HPLC and mass spectrometry. Available exclusively for in vitro and laboratory research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

N-Acetyl Epithalon Amidate represents a next-generation structural refinement of the well-characterized tetrapeptide Epitalon (Ala-Glu-Asp-Gly). By introducing an acetyl group at the N-terminus and an amide group at the C-terminus, this analog achieves substantially improved resistance to enzymatic degradation compared to its unmodified parent compound. The Peptide Store supplies this compound to qualified research institutions and independent laboratories seeking a high-integrity tool for investigations into cellular senescence, genomic stability, and epigenetic regulation. Its enhanced structural profile makes it a preferred reference compound for studies where peptide half-life and conformational integrity are critical experimental variables.

Peptide Structure & Amino Acid Sequence

The core sequence of N-Acetyl Epithalon Amidate is derived from the naturally occurring pineal tetrapeptide Epitalon, with the amino acid sequence Ala-Glu-Asp-Gly. The modification involves acetylation at the alpha-amino group of the N-terminal alanine residue and amidation at the C-terminal glycine carboxyl group. These dual terminal modifications collectively confer superior proteolytic resistance and improved aqueous solubility profiles, both of which are highly relevant to controlled in vitro research environments. The molecular architecture is precisely defined to ensure batch-to-batch reproducibility across all units supplied by The Peptide Store.

Chemical & Physical Characteristics

• Peptide Base: Epitalon analog (Ala-Glu-Asp-Gly)
• Modifications: N-terminal acetylation; C-terminal amidation
• Molecular Formula: C₁₄H₂₂N₄O₉
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and standard laboratory solvents
• Stability: Enhanced enzymatic resistance due to dual terminal modifications
• Storage Form: Lyophilized solid for extended shelf stability

Purity & Analytical Verification (HPLC & MS)

Every batch of N-Acetyl Epithalon Amidate supplied by The Peptide Store undergoes rigorous analytical testing prior to release. Purity is confirmed at ≥98% using high-performance liquid chromatography (HPLC), with identity verification performed via mass spectrometry (MS). These dual analytical methods ensure that the peptide sequence, molecular weight, and chemical integrity all conform to the defined specifications. Researchers can confidently rely on the documented purity and identity data when designing experiments that require precise compound characterization. Certificate of Analysis (CoA) documentation is available upon request for all product lots.

Quality Control & Lyophilization Integrity

The Peptide Store applies pharmaceutical-grade lyophilization protocols to all research peptides, including N-Acetyl Epithalon Amidate. Lyophilization removes residual moisture under controlled vacuum and temperature conditions, producing a stable, low-moisture powder that maintains structural integrity during transit and storage. Each vial is sealed under inert gas conditions to minimize oxidative degradation. Internal quality control checkpoints are applied throughout synthesis, purification, and packaging to ensure that every unit reaching the researcher meets the highest standards of consistency and purity.

Safety, Handling & Laboratory Precautions

This compound is intended solely for use by trained laboratory professionals in controlled research settings. Standard laboratory safety protocols must be observed at all times when handling this peptide. Appropriate personal protective equipment (PPE), including gloves, eye protection, and lab coat, should be worn. This material has not been evaluated for safety in biological systems and must not be administered to humans or animals under any circumstances. Researchers should consult applicable institutional safety guidelines and dispose of all materials in accordance with local regulatory requirements for research chemicals.

Reconstitution, Packaging & Storage

N-Acetyl Epithalon Amidate is supplied as a lyophilized powder in sealed, clearly labeled research vials. For laboratory reconstitution purposes, sterile aqueous buffers appropriate to the intended assay system should be selected based on the researcher’s experimental protocol. Upon reconstitution, solutions should be aliquoted and stored according to standard peptide handling procedures. Lyophilized product should be stored at −20°C or below, protected from light and moisture. Reconstituted solutions should be used promptly or stored at −80°C to preserve integrity. Avoid repeated freeze-thaw cycles to maintain compound stability.

Intended Research Use & Market Positioning

N-Acetyl Epithalon Amidate is positioned as a premium research tool for laboratories focused on telomerase biology, epigenetic aging mechanisms, genomic stability, and pineal peptide pharmacology. Its dual terminal modifications make it particularly suitable for comparative studies against unmodified Epitalon, offering researchers a chemically distinct analog with enhanced stability characteristics. The Peptide Store offers this compound for sale to academic institutions, pharmaceutical research organizations, and independent research laboratories operating under appropriate regulatory frameworks.

Ordering, Availability & Fulfillment

Buy N-Acetyl Epithalon Amidate online directly through The Peptide Store for fast, reliable fulfillment. Orders are processed promptly and shipped with appropriate cold-chain packaging to preserve lyophilized integrity during transit. The Peptide Store offers competitive best-price positioning on all research peptides, with bulk ordering options available for qualifying institutions. Order now to secure verified, HPLC-MS confirmed N-Acetyl Epithalon Amidate for your research program.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. N-Acetyl Epithalon Amidate is sold exclusively as a laboratory research reagent. It has not been approved by any regulatory authority for therapeutic, prophylactic, or diagnostic use. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international laws governing the acquisition and use of research chemicals. The Peptide Store assumes no liability for misuse of this compound beyond its stated research purpose.