KPV Peptide (Ac-KPV-NH2) 5mg

KPV Peptide (Ac-KPV-NH2) is a premium-grade synthetic tripeptide available at ≥98% purity, supplied by The Peptide Store exclusively as a biochemical research tool. Derived structurally from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH), this capped tripeptide analog offers researchers a highly stable molecular probe for investigating inflammatory signaling, NF-κB pathway modulation, and antimicrobial mechanisms in controlled laboratory settings. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

KPV Peptide (Ac-KPV-NH2) is a highly specialized synthetic tripeptide engineered to function as a precise molecular probe in immunology, inflammatory biology, and cellular homeostasis research. Its structural correspondence to the C-terminal domain of endogenous α-MSH makes it a compelling subject of investigation for researchers studying melanocortin-related signaling pathways. Critically, KPV does not engage the Melanocortin-1 Receptor (MC1R) responsible for melanin synthesis, allowing investigators to study downstream inflammatory modulation in isolation. Available for sale at The Peptide Store, this compound is intended strictly for qualified laboratory professionals conducting non-clinical research.

Peptide Structure & Amino Acid Sequence

The full chemical designation of KPV Peptide is Ac-Lys-Pro-Val-NH₂, representing a tripeptide composed of lysine, proline, and valine residues. The compound is distinguished by its dual end-capping architecture: an N-terminal acetyl group and a C-terminal amide group. This molecular capping strategy significantly enhances structural resilience against exopeptidase-mediated degradation, extending the compound’s functional window in in vitro experimental environments. The sequence mirrors the extreme C-terminal tripeptide of α-MSH (positions 11–13), a region associated with potent immunomodulatory activity independent of classical melanocortin receptor engagement.

Chemical & Physical Characteristics

• Peptide Name: KPV (Ac-KPV-NH2)
• Sequence: Ac-Lys-Pro-Val-NH₂
• Molecular Formula: C₁₈H₃₃N₅O₄
• Molecular Weight: Approximately 383.49 g/mol
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and standard laboratory solvents
• Purity: ≥98% as verified by HPLC and mass spectrometry

The compact tripeptide architecture, combined with end-capping, contributes to enhanced physicochemical stability compared to unmodified linear analogs, making KPV a reliable and reproducible tool for controlled experimental use.

Purity & Analytical Verification (HPLC & MS)

Every batch of KPV Peptide (Ac-KPV-NH2) supplied by The Peptide Store is manufactured to a minimum purity threshold of ≥98%, verified through rigorous analytical protocols. High-Performance Liquid Chromatography (HPLC) is employed to confirm compound identity and quantify impurity profiles, while Mass Spectrometry (MS) validates the precise molecular mass and confirms structural integrity. Researchers can order with confidence knowing that each vial meets the highest analytical standards required for reproducible, publication-quality laboratory investigations.

Quality Control & Lyophilization Integrity

KPV Peptide is produced under stringent quality control conditions and supplied in lyophilized (freeze-dried) form to maximize long-term stability. The lyophilization process removes residual moisture, protecting the peptide’s structural conformation and biochemical activity during storage and transit. Each unit undergoes batch-level quality review prior to fulfillment, ensuring that the compound delivered to your laboratory meets documented purity and integrity specifications. Certificate of Analysis (CoA) documentation is available upon request.

Safety, Handling & Laboratory Precautions

As with all research-grade peptides, KPV (Ac-KPV-NH2) should be handled exclusively by trained laboratory personnel in appropriately equipped research facilities. Standard laboratory safety protocols apply, including the use of personal protective equipment (PPE) such as gloves, lab coats, and eye protection. This compound is not intended for human or veterinary use and must not be administered to any living organism. Researchers should consult applicable institutional biosafety guidelines before working with this material. Dispose of unused material in accordance with local regulatory requirements for laboratory chemical waste.

Reconstitution, Packaging & Storage

KPV Peptide is supplied as a lyophilized powder in a sealed, research-grade vial. For laboratory reconstitution, researchers should use sterile aqueous buffers or appropriate organic solvents consistent with the experimental protocol being employed. Reconstitution should be performed under aseptic conditions using standard laboratory techniques. Store the lyophilized product at -20°C in a dry, dark environment away from repeated freeze-thaw cycles to preserve optimal stability. Once reconstituted, solutions should be aliquoted and stored according to established laboratory best practices.

Intended Research Use & Market Positioning

KPV Peptide (Ac-KPV-NH2) is positioned as a premium biochemical research tool for investigators exploring NF-κB signaling downregulation, innate immune modulation, antimicrobial peptide mechanisms, and epithelial barrier biology. Its unique structural profile—derived from α-MSH yet independent of MC1R activation—makes it an attractive compound for comparative studies in melanocortin biology and inflammatory pathway dissection. The Peptide Store offers this compound at a competitive best price, making high-purity KPV accessible to academic institutions, contract research organizations, and independent research laboratories worldwide.

Ordering, Availability & Fulfillment

KPV Peptide (Ac-KPV-NH2) is available to buy online now directly through The Peptide Store. Orders are processed promptly, with fast fulfillment and discreet, secure packaging to maintain product integrity during transit. Our customer support team is available to assist with bulk inquiries, institutional purchase orders, and CoA requests. Order now to secure your supply of this high-demand research peptide at the best price available.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. KPV Peptide (Ac-KPV-NH2) is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding the therapeutic, prophylactic, or diagnostic utility of this compound. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international laws and regulations governing the procurement, storage, and use of research peptides. This product must not be used in any manner inconsistent with its research-only designation.