Tesofensine 500mcg (30 Capsules)

Tesofensine 500mcg (30 Capsules) is a research-grade triple monoamine reuptake inhibitor supplied at ≥98% purity, formulated exclusively for in vitro and laboratory research applications. Each capsule delivers a precisely measured dose, providing investigators with a consistent, analytically verified research tool for studying dopamine, serotonin, and noradrenaline transporter systems. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Available now at The Peptide Store, Tesofensine 500mcg (30 Capsules) occupies a singular position within the landscape of neurochemical and metabolic research compounds. As a pharmacologically distinct triple monoamine reuptake inhibitor — simultaneously engaging the dopamine transporter (DAT), serotonin transporter (SERT), and noradrenaline transporter (NET) — this compound provides researchers with a powerful tool for modeling the intersecting neurochemical pathways that govern energy homeostasis, appetitive behavior, and central nervous system monoamine dynamics. Originally investigated within the neurodegenerative disease research context, Tesofensine subsequently attracted significant scientific interest in metabolic and neuro-endocrinological research settings, making it one of the most studied small-molecule compounds in contemporary preclinical science.

Peptide Structure & Amino Acid Sequence

Tesofensine is not a peptide in the classical amino acid chain sense but rather a small-molecule bicyclic compound classified as a phenyltropane derivative. Its IUPAC designation is (1R,2S,3S,5S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester, with the molecular formula C₁₅H₁₉Cl₂NO₂ and a molecular weight of approximately 320.22 g/mol. The CAS number commonly associated with Tesofensine is 195875-84-4. Its bicyclic tropane scaffold is structurally responsible for its high-affinity binding to all three monoamine transporter subtypes, distinguishing it from selective reuptake inhibitors that target only one transporter system.

Chemical & Physical Characteristics

Tesofensine presents as a white to off-white crystalline powder in its pure form. It exhibits moderate lipophilicity, facilitating effective CNS penetration in research models. Key physicochemical parameters include a calculated LogP in the range of 2.8–3.4, indicating balanced aqueous solubility and membrane permeability. The compound is stable under standard laboratory conditions and demonstrates favorable compatibility with standard oral capsule excipients, making the encapsulated format particularly suitable for controlled preclinical administration studies.

• Molecular Formula: C₁₅H₁₉Cl₂NO₂
• Molecular Weight: ~320.22 g/mol
• CAS Number: 195875-84-4
• Appearance: White to off-white crystalline powder
• Mechanism Class: Triple monoamine reuptake inhibitor (DAT/SERT/NET)

Purity & Analytical Verification (HPLC & MS)

Every batch of Tesofensine 500mcg capsules supplied by The Peptide Store is manufactured to a minimum purity of ≥98%, confirmed through rigorous analytical testing. High-Performance Liquid Chromatography (HPLC) is employed to quantify purity and detect trace impurities, while Mass Spectrometry (MS) confirms molecular identity and structural integrity. Certificates of Analysis (CoA) reflecting these results are available upon request, ensuring full analytical transparency for research institutions and independent investigators.

Quality Control & Lyophilization Integrity

Unlike lyophilized peptide powders, Tesofensine in capsule form undergoes a specialized encapsulation quality control process. Each capsule is uniformly filled to the stated 500mcg dose using precision dispensing equipment, with batch-level weight uniformity testing conducted to ensure dosing consistency across all 30 capsules per unit. Capsules are sealed in pharmaceutical-grade gelatin shells and packaged to minimize exposure to moisture, light, and oxidative stress — all critical factors for maintaining compound stability throughout the product’s shelf life.

Safety, Handling & Laboratory Precautions

Tesofensine is a pharmacologically active research compound and must be handled with appropriate laboratory precautions. Researchers should wear suitable personal protective equipment (PPE) including nitrile gloves, eye protection, and lab coats when handling. Avoid inhalation of powder or dust during any transfer procedures. This compound is strictly intended for controlled laboratory environments by trained scientific personnel only. All handling, storage, and disposal must comply with applicable institutional biosafety guidelines and local regulatory requirements.

Reconstitution, Packaging & Storage

Tesofensine 500mcg capsules require no reconstitution and are supplied ready for laboratory use in their encapsulated format. Each unit contains 30 capsules, individually sealed within a secure, tamper-evident container. For optimal stability, store at 2–8°C in a dry, dark environment away from direct light and humidity. When stored correctly, the product maintains its labeled purity and potency throughout the stated shelf life. Do not freeze capsule formats unless specifically indicated by your institutional protocols.

Intended Research Use & Market Positioning

Tesofensine 500mcg (30 Capsules) is intended exclusively for in vitro laboratory research and preclinical investigation. It is particularly relevant for researchers studying monoaminergic neurotransmission, central appetite regulation, energy expenditure modeling, and the intersection of dopaminergic and serotonergic signaling pathways. The Peptide Store positions this compound as a premium, analytically verified research tool for academic institutions, contract research organizations (CROs), and independent laboratories requiring reliable, high-purity small molecules for advanced neurochemical and metabolic studies.

Ordering, Availability & Fulfillment

Tesofensine 500mcg (30 Capsules) is available to buy online now at The Peptide Store with competitive best-price positioning and streamlined order fulfillment. We offer secure checkout, discreet laboratory-grade packaging, and prompt dispatch to qualified research institutions and licensed investigators. Order now to take advantage of our fast processing times and dedicated customer support team. Bulk research quantities and institutional procurement inquiries are welcomed — contact our team directly for volume pricing and availability.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Tesofensine 500mcg (30 Capsules) is sold exclusively as a laboratory research compound. The Peptide Store makes no representations regarding its suitability for therapeutic, diagnostic, or any other non-research application. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the purchase, possession, and use of research compounds. This product is not a drug, supplement, or food product and has not been evaluated or approved by any regulatory authority for human or animal use.