AOD9604 Peptide 6mg

AOD9604 is a high-purity synthetic peptide analogue derived from the lipolytic domain of human growth hormone (hGH), specifically mimicking the C-terminal fragment hGH₁₇₇₋₁₉₁ with an additional tyrosine residue. Available at ≥98% purity, this 6mg configuration serves as a precise biochemical research tool for investigating non-diabetogenic fat metabolism, beta-3 adrenergic receptor interactions, and chondrocyte regeneration without altering systemic IGF-1 pathways. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

AOD9604 — also referenced in early pharmacological literature as Advanced Obesity Drug-9604 — is a modified disulfide-bonded cyclic peptide engineered to isolate the lipolytic properties of somatotropin from its broader anabolic configurations. Developed as a specialized molecular probe, AOD9604 has become a widely studied compound in metabolic endocrinology, adipocyte signaling, and tissue-remodeling research. The Peptide Store offers this compound in a 6mg format, providing researchers with a sufficient quantity for multi-assay experimental protocols. Its structural design allows investigators to study lipid oxidation pathways, adipocyte receptor dynamics, and cartilage matrix repair kinetics with a high degree of specificity and experimental control.

Peptide Structure & Amino Acid Sequence

AOD9604 is a disulfide-bonded cyclic peptide fragment corresponding to residues 177–191 of human growth hormone, with a tyrosine residue appended at the N-terminus. This structural modification stabilizes the peptide’s secondary conformation and enhances receptor selectivity. The disulfide bridge between cysteine residues at positions 182 and 189 (relative to native hGH numbering) maintains the cyclic topology essential for its interaction with beta-3 adrenergic receptors. The amino acid sequence is: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. This sequence confers selective lipolytic activity while dissociating the compound from the insulin-desensitizing effects associated with full-length hGH administration, making it an invaluable tool in controlled metabolic research settings.

Chemical & Physical Characteristics

• Molecular Formula: C₇₈H₁₃₃N₂₃O₂₃S₂
• Molecular Weight: Approximately 1,817.1 Da
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and dilute acetic acid solutions
• CAS Number: 221231-10-3
• Classification: Synthetic cyclic peptide fragment; hGH C-terminal analogue

These physical characteristics make AOD9604 compatible with a wide range of in vitro and ex vivo laboratory methodologies, including receptor binding assays, lipid metabolism panels, and cartilage tissue modeling experiments.

Purity & Analytical Verification (HPLC & MS)

Every batch of AOD9604 available through The Peptide Store is manufactured to a minimum purity of ≥98%, verified through reverse-phase high-performance liquid chromatography (RP-HPLC). Mass spectrometry (MS) confirmation is performed in parallel to authenticate molecular weight integrity and confirm the absence of truncated sequences, oxidized byproducts, or residual synthesis impurities. These dual-verification protocols ensure that each vial meets the rigorous analytical standards required for reproducible, publication-quality research outcomes.

Quality Control & Lyophilization Integrity

AOD9604 is produced under stringent quality control conditions consistent with research-grade peptide manufacturing standards. Following synthesis and purification, the peptide undergoes lyophilization — a freeze-drying process that removes residual moisture and stabilizes the compound’s structural integrity over extended storage periods. Each vial is sealed under inert atmospheric conditions to prevent oxidative degradation of the disulfide bond and to preserve the cyclic conformation critical to the peptide’s biological activity in research assays. Lot-specific certificates of analysis (CoA) are available upon request.

Safety, Handling & Laboratory Precautions

AOD9604 is intended exclusively for use by trained laboratory personnel in certified research environments. Standard laboratory precautions apply: use appropriate personal protective equipment (PPE) including gloves, eye protection, and lab coat when handling. Avoid inhalation of lyophilized powder. This compound is not classified as a hazardous substance under standard laboratory safety frameworks; however, all handling should comply with institutional biosafety guidelines and applicable local regulations. This product is not approved for any in vivo, clinical, or consumptive application.

Reconstitution, Packaging & Storage

AOD9604 is supplied as a sterile lyophilized powder in sealed research-grade vials. For laboratory reconstitution, researchers typically employ sterile aqueous buffers or dilute acetic acid solutions appropriate for their specific assay requirements — always in accordance with institutional protocols. Upon reconstitution, the peptide solution should be aliquoted and stored at −20°C or below to maintain stability. Lyophilized stock should be stored at −20°C in a dry, dark environment, protected from repeated freeze-thaw cycles. Shelf life of the lyophilized form is up to 24 months under recommended storage conditions.

Intended Research Use & Market Positioning

AOD9604 6mg is positioned as a premium research-grade compound for investigators working in metabolic endocrinology, adipocyte biology, beta-adrenergic pharmacology, and musculoskeletal tissue research. Its unique ability to stimulate lipolysis and inhibit lipogenesis without engaging the IGF-1 axis makes it a highly selective tool for dissecting the independent lipolytic mechanisms of growth hormone signaling. Researchers studying chondrocyte regeneration and osteoarthritis models have also employed AOD9604 as a cartilage matrix repair probe in ex vivo tissue assays.

Ordering, Availability & Fulfillment

The Peptide Store offers AOD9604 6mg for sale online with competitive pricing, reliable stock availability, and prompt order fulfillment. Buy AOD9604 online with confidence through our secure checkout platform. Orders are processed efficiently and dispatched with appropriate cold-chain packaging to preserve peptide integrity during transit. For bulk research orders or institutional procurement inquiries, contact our team directly for best price options and volume availability.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. AOD9604 is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding therapeutic efficacy, safety for administration, or suitability for any use beyond controlled in vitro and ex vivo research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the procurement and use of research peptides. This product has not been evaluated or approved by the FDA or any equivalent regulatory authority for medical use.