B7-33 (Relaxin Analog) 6mg

B7-33 (Relaxin Analog) is a premium-grade, synthetic single-chain peptide analogue of human gene-2 relaxin (H2 relaxin), manufactured to ≥98% purity and supplied in lyophilized form by The Peptide Store. Engineered as a high-resolution biochemical tool, B7-33 enables investigators to probe RXFP1 receptor signaling, matrix metalloproteinase (MMP) activation, and tissue-specific anti-fibrotic kinetics with exceptional molecular precision. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

B7-33 represents a significant structural advancement over native H2 relaxin. While endogenous H2 relaxin is a complex, dual-chain disulfide-linked hormone presenting notable synthesis and long-term stability challenges, B7-33 is derived from a truncated, linear segment of the native receptor-binding domain. This single-chain architecture preserves the key pharmacophoric elements responsible for RXFP1 receptor engagement while eliminating structural liabilities associated with the full-length hormone. The result is a chemically tractable, highly stable research compound that The Peptide Store is proud to offer at competitive pricing for qualified laboratory researchers worldwide.

Peptide Structure & Amino Acid Sequence

B7-33 is a linear, single-chain peptide derived from the B-chain segment of human relaxin-2 (H2 relaxin). By isolating and optimizing the receptor-binding motif within the native B-chain, B7-33 retains selective RXFP1 agonist activity without the structural complexity of the intact heterodimeric hormone. This streamlined architecture facilitates reproducible solid-phase peptide synthesis (SPPS), enabling consistent batch-to-batch fidelity and superior analytical characterization. The absence of inter-chain disulfide bonds also reduces conformational variability, making B7-33 a more tractable tool for mechanistic in vitro and in vivo research models.

Chemical & Physical Characteristics

• Type: Synthetic single-chain linear peptide analogue
• Target Receptor: RXFP1 (Relaxin Family Peptide Receptor 1)
• Biological Basis: Derived from the B-chain of human gene-2 relaxin (H2 relaxin)
• Purity: ≥98% (HPLC-verified)
• Form: Lyophilized white to off-white powder
• Solubility: Soluble in aqueous buffers; specific solubility conditions should be determined empirically within the research context
• Storage Temperature: −20°C (long-term); −80°C for extended archival storage
• Research Applications: Cardiovascular remodeling, fibrosis biology, pulmonology, gestational vascular mechanics, MMP pathway investigation

Purity & Analytical Verification (HPLC & MS)

Every batch of B7-33 supplied by The Peptide Store undergoes rigorous analytical verification prior to release. High-performance liquid chromatography (HPLC) is employed to confirm chromatographic purity at ≥98%, ensuring that each vial contains a highly homogeneous active peptide fraction with minimal impurity profiles. Mass spectrometry (MS) analysis independently confirms molecular identity by validating the observed molecular weight against the theoretical mass of the B7-33 sequence. Researchers can request batch-specific Certificates of Analysis (CoA) confirming both HPLC purity data and MS identity confirmation, providing full analytical traceability for publication-quality research.

Quality Control & Lyophilization Integrity

B7-33 is lyophilized under controlled conditions to remove residual moisture and maximize long-term structural integrity. Lyophilization preserves peptide conformation, prevents hydrolytic degradation, and extends shelf life under appropriate cold-chain storage conditions. Quality control protocols at The Peptide Store encompass raw material verification, in-process monitoring, and final product release testing. Each vial is sealed under inert atmosphere to prevent oxidative degradation and is labeled with full batch traceability information. These stringent quality measures ensure that researchers receive a product that meets the highest standards of biochemical reliability.

Safety, Handling & Laboratory Precautions

B7-33 is supplied exclusively for qualified laboratory research use. Personnel handling this compound should adhere to standard laboratory safety protocols, including the use of appropriate personal protective equipment (PPE) such as gloves, lab coat, and eye protection. As a research-grade peptide, B7-33 should be handled in a controlled laboratory environment by trained scientific personnel. Avoid inhalation of lyophilized powder. Dispose of all materials in accordance with applicable institutional and regulatory waste disposal guidelines. This compound has not been evaluated for safety in humans or animals and must not be used outside of a regulated research context.

Reconstitution, Packaging & Storage

B7-33 is packaged in sterile, sealed vials suitable for laboratory research workflows. Reconstitution protocols should be established by qualified researchers according to the specific requirements of their experimental systems. General guidance suggests dissolving lyophilized peptide in an appropriate aqueous buffer; however, all reconstitution decisions must be made within the research laboratory context and are the sole responsibility of the investigator. Upon reconstitution, aliquot immediately to avoid repeated freeze-thaw cycles, which may compromise peptide integrity. Store lyophilized material at −20°C and protect from light and humidity. Reconstituted solutions should be stored at −80°C if not used immediately.

Intended Research Use & Market Positioning

B7-33 occupies a unique niche in the research peptide market as a structurally simplified, RXFP1-selective relaxin analogue with documented utility in cardiovascular, fibrotic, pulmonary, and gestational vascular research models. Its single-chain design eliminates tumor-promoting cascade activation reported with certain full-length relaxin constructs, making it a preferred molecular tool for investigators studying anti-fibrotic pathways without off-target proliferative signaling. The Peptide Store offers B7-33 at competitive best-price positioning, backed by full analytical documentation, making it an ideal choice for academic institutions, contract research organizations (CROs), and independent research laboratories seeking to buy high-purity relaxin analog peptides online.

Ordering, Availability & Fulfillment

B7-33 (Relaxin Analog) is available for sale online through The Peptide Store with streamlined ordering, fast fulfillment, and international shipping options for qualified research institutions. Order now to take advantage of our best-price guarantee on research-grade peptides. All orders are processed with full batch traceability and shipped with accompanying analytical documentation. For bulk orders, institutional procurement, or custom quantity inquiries, contact The Peptide Store directly through our official store channels.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. B7-33 (Relaxin Analog) is sold exclusively as a laboratory research reagent. It has not been approved by the FDA, EMA, or any other regulatory authority for therapeutic, diagnostic, or prophylactic use in humans or animals. Purchasers assume full responsibility for compliance with all applicable local, national, and international laws and regulations governing the acquisition, handling, storage, and use of research peptides. The Peptide Store makes no representations regarding the suitability of this compound for any application beyond qualified laboratory research.