TB-500 (Thymosin Beta-4) 10mg (43aa)

TB-500 (Thymosin Beta-4) 10mg (43aa) is a high-concentration, full-sequence synthetic peptide supplied at ≥98% purity by The Peptide Store. This lyophilized vial delivers the complete 43-amino acid chain essential for advanced laboratory investigation of actin dynamics, cytoskeletal organization, and cellular motility signaling pathways. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

TB-500, the synthetic analog of endogenous Thymosin Beta-4, is one of the most extensively studied peptides in modern molecular biology research. As the primary intracellular G-actin sequestering protein, it plays a central regulatory role in cytoskeletal dynamics across virtually all mammalian cell types. The Peptide Store offers this 10mg presentation to support longitudinal, high-resolution experimental protocols where consistent peptide concentration and formulation stability are critical requirements. Researchers investigating tissue remodeling, cellular migration, and actin polymerization mechanisms will find this full 43-amino acid sequence indispensable for generating reproducible, publication-quality data.

Peptide Structure & Amino Acid Sequence

TB-500 encompasses the complete 43-amino acid sequence of Thymosin Beta-4, a highly conserved protein expressed ubiquitously in mammalian cells. The sequence includes the canonical LKKTET actin-binding motif responsible for its interaction with monomeric G-actin. Unlike truncated fragments or partial analogs, the full-length 43aa structure preserves the pleiotropic signaling capacity of the native protein, enabling researchers to study the complete range of molecular interactions associated with this peptide in cellular and biochemical assay systems.

Chemical & Physical Characteristics

• Peptide Name: TB-500 (Thymosin Beta-4)
• Sequence Length: 43 Amino Acids (43aa)
• Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
• Molecular Weight: Approximately 4,963 Da
• CAS Number: 77591-33-4
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffer systems; for laboratory use only
• Storage Temperature: −20°C (long-term); 2–8°C (short-term)

Purity & Analytical Verification (HPLC & MS)

Every batch of TB-500 supplied by The Peptide Store undergoes rigorous analytical verification to confirm ≥98% purity. High-Performance Liquid Chromatography (HPLC) is used to assess peptide homogeneity and detect trace impurities, while Mass Spectrometry (MS) confirms the correct molecular weight and sequence integrity of the full 43-amino acid chain. These dual analytical methods ensure that each vial meets the stringent quality benchmarks required for reproducible preclinical and in vitro research applications.

Quality Control & Lyophilization Integrity

TB-500 from The Peptide Store is produced using pharmaceutical-grade lyophilization processes that preserve the structural integrity and biological activity profile of the peptide under laboratory conditions. Lyophilization removes residual moisture to extend shelf life and maintain molecular stability during storage and transit. Each vial is sealed under inert conditions to prevent oxidation and contamination, ensuring that researchers receive a product that performs consistently across all experimental replicates.

Safety, Handling & Laboratory Precautions

This peptide is intended exclusively for qualified laboratory professionals operating within appropriately equipped research facilities. Standard laboratory safety protocols must be observed at all times when handling this compound. Appropriate personal protective equipment (PPE), including gloves, eye protection, and lab coats, should be worn. This material is not approved for any biological, clinical, or in-human application. Researchers should consult applicable institutional safety guidelines and local regulatory frameworks before commencing any experimental work involving this compound.

Reconstitution, Packaging & Storage

TB-500 is supplied as a lyophilized powder in a sealed research-grade vial. Reconstitution should be performed using sterile aqueous solvents appropriate for the intended in vitro or biochemical assay format, strictly within a laboratory setting by trained personnel. Once reconstituted, the peptide solution should be aliquoted and stored according to standard laboratory protocols to minimize freeze-thaw degradation. Unopened vials should be stored at −20°C for long-term preservation and kept away from light, moisture, and heat sources.

Intended Research Use & Market Positioning

TB-500 (Thymosin Beta-4) 10mg is positioned as a premium research tool for scientists studying actin polymerization, cytoskeletal remodeling, and intracellular signaling cascades. Its well-characterized molecular profile makes it a preferred reference peptide in proteomics, cell biology, and biochemical assay development. The Peptide Store offers this compound at a competitive best price, making it accessible to academic institutions, contract research organizations, and independent laboratories seeking reliable, high-purity peptide reagents for sale online.

Ordering, Availability & Fulfillment

Buy TB-500 (Thymosin Beta-4) 10mg online today through The Peptide Store with confidence. We maintain consistent inventory availability and offer streamlined order processing to ensure rapid fulfillment. Our secure checkout supports multiple payment options, and all orders are dispatched with appropriate cold-chain packaging to protect peptide integrity during transit. Order now to take advantage of our best price guarantee and experience the reliable service that research professionals trust.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. TB-500 (Thymosin Beta-4) is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding therapeutic efficacy, biological safety in humans or animals, or suitability for any application outside of controlled laboratory research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the acquisition, possession, and use of research peptides. This product has not been evaluated or approved by any regulatory authority for human or veterinary use.