Syn-Coll (Palmitoyl Tripeptide-5) 200mg (Topical)

Syn-Coll (Palmitoyl Tripeptide-5) is a high-purity synthetic cosmetic research peptide supplied by The Peptide Store at ≥98% purity, verified by HPLC and mass spectrometry. Formulated for topical research applications, this compound is intended exclusively for in vitro and laboratory research contexts. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Syn-Coll, commercially identified as Palmitoyl Tripeptide-5, is a lipopeptide composed of a palmitoyl fatty acid chain conjugated to a tripeptide sequence. It has attracted significant interest in cosmetic biochemistry and dermatological research due to its structural relationship with the thrombospondin-1 (TSP-1) activation pathway, which is associated with transforming growth factor-beta (TGF-β) signaling involved in extracellular matrix modulation. Researchers investigating collagen biosynthesis, skin matrix biology, and peptide-lipid conjugation mechanisms frequently source this compound for controlled laboratory studies. The Peptide Store offers this compound for sale to qualified research institutions and laboratory professionals seeking a reliable, analytically verified supply.

Peptide Structure & Amino Acid Sequence

Palmitoyl Tripeptide-5 is a palmitoylated tripeptide built on the core sequence Lys-Val-Lys (KVK), with a C16 palmitoyl fatty acid chain attached at the N-terminus. This lipid conjugation significantly enhances the compound’s affinity for biological membranes and improves its stability in formulated research preparations. The tripeptide backbone mimics a region of TSP-1 that is known to interact with latent TGF-β complexes, making it a structurally relevant tool for studying peptide-receptor interactions in matrix biology research contexts.

Chemical & Physical Characteristics

• Common Name: Syn-Coll / Palmitoyl Tripeptide-5
• Peptide Sequence: Palmitoyl-Lys-Val-Lys
• Molecular Formula: C₃₀H₅₉N₅O₄
• Molecular Weight: Approximately 569.83 g/mol
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and common cosmetic carrier solvents (research-grade)
• Application Format: Topical research use
• Purity: ≥98% (HPLC verified)

Purity & Analytical Verification (HPLC & MS)

Every batch of Syn-Coll (Palmitoyl Tripeptide-5) supplied by The Peptide Store undergoes rigorous analytical testing prior to dispatch. Purity is confirmed at ≥98% using reverse-phase high-performance liquid chromatography (RP-HPLC), and molecular identity is validated through mass spectrometry (MS). These dual verification methods ensure that researchers receive a compound of consistent quality suitable for reproducible experimental outcomes. Certificates of Analysis (CoA) are available upon request and accompany each order to support research documentation requirements.

Quality Control & Lyophilization Integrity

Syn-Coll is produced under controlled manufacturing conditions and supplied in lyophilized (freeze-dried) form to maximize shelf stability and minimize degradation during transit and storage. The lyophilization process removes residual moisture, preserving the structural integrity of the palmitoyl-tripeptide conjugate. Each unit is sealed under inert conditions to prevent oxidative or hydrolytic degradation. The Peptide Store’s quality control protocols include batch-level documentation and traceability, ensuring that every product dispatched meets the declared specification of ≥98% purity.

Safety, Handling & Laboratory Precautions

As with all research-grade peptide compounds, Syn-Coll (Palmitoyl Tripeptide-5) should be handled exclusively by trained laboratory personnel in appropriately equipped research facilities. Standard laboratory safety precautions apply, including the use of personal protective equipment (PPE) such as gloves, eye protection, and lab coats. This compound must not be used on humans or animals under any circumstances. It is not approved for clinical, therapeutic, or diagnostic use. Researchers should consult applicable institutional biosafety guidelines and local regulatory frameworks before commencing any experimental work involving this material.

Reconstitution, Packaging & Storage

For topical research formulation studies, Syn-Coll may be reconstituted in appropriate research-grade solvents or aqueous carriers as determined by the laboratory protocol in use. Researchers should consult peer-reviewed literature to identify suitable carrier systems for their specific experimental design. Upon receipt, the lyophilized powder should be stored at -20°C in a dry, dark environment, away from repeated freeze-thaw cycles. Once reconstituted for research purposes, preparations should be handled according to the stability data relevant to the solvent system employed. Packaging is designed to maintain compound integrity throughout shipping and short-term laboratory storage.

Intended Research Use & Market Positioning

Syn-Coll (Palmitoyl Tripeptide-5) is positioned as a premium-grade topical research peptide for academic institutions, cosmetic ingredient researchers, and biochemistry laboratories investigating extracellular matrix dynamics, collagen synthesis pathways, and lipopeptide bioactivity. It is not intended for formulation into consumer products, nor for any use outside of a controlled research environment. The Peptide Store offers this compound at a competitive best price, making it accessible to research teams requiring consistent, high-purity supply for ongoing studies.

Ordering, Availability & Fulfillment

Researchers can conveniently buy Syn-Coll (Palmitoyl Tripeptide-5) online directly through The Peptide Store. Orders are processed promptly, with secure packaging and tracked fulfillment to ensure safe delivery to your laboratory. Our streamlined ordering system is designed to support research procurement workflows, and our team is available to assist with bulk inquiries, CoA requests, and order status updates. Order now to take advantage of our reliable stock availability and competitive pricing.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Syn-Coll (Palmitoyl Tripeptide-5) is sold exclusively as a laboratory research compound. The Peptide Store makes no therapeutic, cosmeceutical, or health-related claims regarding this product. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the procurement, storage, and use of research peptides. This product is not approved by any regulatory authority for use in humans, animals, or consumer-facing applications.