GHK Basic 50mg

GHK Basic 50mg (Tripeptide-1, Glycyl-L-Histidyl-L-Lysine) is a premium-grade, uncomplexed signal peptide manufactured to ≥98% purity and supplied by The Peptide Store for advanced genomic, regenerative, and extracellular matrix (ECM) remodeling research. This formulation serves as a high-resolution biochemical tool for investigating cell signaling cascades, metal-chelating affinity mechanics, and age-associated cellular decline. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

GHK Basic, biochemically classified as Tripeptide-1, is a naturally occurring signal peptide found endogenously within human plasma. Unlike its copper-complexed counterpart (GHK-Cu), GHK Basic represents the pure, uncomplexed base tripeptide sequence — Glycyl-L-Histidyl-L-Lysine — making it a uniquely independent cellular messenger. This uncomplexed form interacts directly with cell surface receptors to stimulate structural signaling cascades without the introduction of a metal cofactor, offering researchers a distinct and controllable variable in experimental design. As organisms age, endogenous concentrations of this bio-identical plasma peptide decline significantly, correlating with reduced systemic tissue repair velocity. GHK Basic is therefore an important subject of inquiry in longevity science, ECM biology, and regenerative research models.

Peptide Structure & Amino Acid Sequence

GHK Basic is a linear tripeptide composed of three amino acid residues in the following sequence: Gly-His-Lys (Glycine – Histidine – Lysine). Its molecular formula is C₁₄H₂₄N₆O₄, with a molecular weight of approximately 340.38 g/mol. The histidine residue at the central position confers the peptide’s characteristic metal-chelating properties, while the lysine terminus contributes to receptor-binding affinity and solubility behavior in aqueous research environments. The absence of a copper ion in GHK Basic allows researchers to isolate and study the peptide’s intrinsic signaling activity independently from metal-mediated effects.

Chemical & Physical Characteristics

• Peptide Name: GHK Basic (Tripeptide-1)
• Sequence: Gly-His-Lys
• Molecular Formula: C₁₄H₂₄N₆O₄
• Molecular Weight: ~340.38 g/mol
• CAS Number: 49557-75-7
• Appearance: White to off-white lyophilized powder or cake
• Solubility: Soluble in aqueous buffers; water-soluble under standard laboratory conditions
• Form: Lyophilized solid
• Purity: ≥98% by HPLC

Purity & Analytical Verification (HPLC & MS)

Every batch of GHK Basic supplied by The Peptide Store is manufactured to a minimum purity threshold of ≥98%, confirmed through high-performance liquid chromatography (HPLC). Mass spectrometry (MS) verification is additionally employed to confirm molecular identity, sequence integrity, and the absence of truncated or miscoupled peptide fragments. These dual-verification protocols ensure that researchers receive a product of consistent, reproducible quality suitable for publication-grade experimental work. Certificates of Analysis (CoA) reflecting these analytical results are available upon request and accompany each order.

Quality Control & Lyophilization Integrity

GHK Basic is produced under stringent quality control conditions aligned with best practices in peptide synthesis and formulation. The lyophilization process is carefully controlled to preserve structural integrity, prevent moisture-induced degradation, and extend long-term stability under proper storage conditions. Each lyophilized cake is visually inspected and weight-verified prior to dispatch. Batch-to-batch consistency is maintained through standardized synthesis protocols, ensuring that researchers at The Peptide Store receive a reliable, reproducible biochemical reference compound across all orders.

Safety, Handling & Laboratory Precautions

GHK Basic is intended exclusively for use by trained laboratory professionals in controlled research environments. Standard laboratory safety protocols must be observed at all times. Researchers should wear appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat, when handling this compound. This peptide is not approved for administration to humans or animals, and must not be used in any clinical, therapeutic, diagnostic, or food-related application. Keep away from unauthorized personnel. Dispose of all materials in accordance with applicable institutional and regulatory waste management guidelines.

Reconstitution, Packaging & Storage

GHK Basic is supplied as a lyophilized solid and should be reconstituted using an appropriate sterile aqueous buffer suitable for the intended in vitro or analytical research application. Reconstitution should be performed under aseptic laboratory conditions using standard peptide handling protocols. Upon receipt, store the lyophilized product at −20°C in a sealed, moisture-protected container away from direct light. Once reconstituted, solutions should be aliquoted, stored at −80°C, and used within a timeframe consistent with established peptide stability data. Avoid repeated freeze-thaw cycles to preserve peptide integrity.

Intended Research Use & Market Positioning

GHK Basic is positioned as a foundational research tool for biochemists, molecular biologists, and dermatological researchers investigating the role of endogenous signal peptides in ECM remodeling, gene expression modulation, cellular senescence, and tissue repair biology. Its uncomplexed form offers a controlled experimental variable not available in copper-chelated formulations, making it especially valuable for mechanistic studies. The Peptide Store supplies GHK Basic to academic institutions, pharmaceutical research laboratories, and independent life science researchers seeking high-purity, analytically verified peptides at competitive pricing.

Ordering, Availability & Fulfillment

GHK Basic 50mg is available to buy online now through The Peptide Store with fast, reliable fulfillment. Our streamlined ordering process ensures that qualified researchers can place an order and receive their compound promptly. We offer competitive best-price guarantees on all research peptides, with secure checkout and discreet, protective packaging to ensure product integrity during transit. For bulk orders or institutional procurement inquiries, please contact our team directly. All orders are subject to verification of intended research use.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. GHK Basic 50mg is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding the safety, efficacy, or suitability of this compound for any use outside of controlled scientific research. Purchasers are solely responsible for ensuring that their acquisition, possession, and use of this product comply with all applicable local, national, and international laws and regulations. By placing an order, the buyer confirms that they are a qualified research professional using this compound for legitimate scientific investigation only.