Pal-GHK 200mg (Palmitoyl Tripeptide-1) (Topical)

Pal-GHK (Palmitoyl Tripeptide-1) is a high-purity, lipid-conjugated research peptide available at ≥98% purity from The Peptide Store. This compound is supplied exclusively as a topical-grade research reagent for qualified laboratory and investigative use. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Pal-GHK, commonly designated Palmitoyl Tripeptide-1, is a fatty acid–conjugated derivative of the tripeptide Glycine-Histidine-Lysine (GHK). The palmitoyl moiety — a 16-carbon saturated fatty acid chain — is covalently attached to the N-terminus of the GHK sequence, substantially enhancing the compound’s lipophilicity. This structural modification has made Pal-GHK a subject of considerable interest in dermatological and cosmetic research contexts, particularly in studies examining extracellular matrix interactions and peptide bioavailability through lipid-rich barrier environments. The Peptide Store supplies this compound to licensed researchers, academic institutions, and qualified laboratory professionals.

Peptide Structure & Amino Acid Sequence

Pal-GHK is a tripeptide composed of three amino acid residues in the following sequence: Glycine – Histidine – Lysine, with a palmitoyl (C16:0) fatty acid chain conjugated to the free alpha-amine at the glycine N-terminus. This lipid conjugation distinguishes Pal-GHK from its unconjugated parent peptide GHK, imparting measurably different physicochemical properties relevant to membrane partitioning and formulation behavior. The molecular formula is C₃₀H₅₄N₆O₅, with a molecular weight of approximately 578.79 g/mol. The CAS number associated with Palmitoyl Tripeptide-1 is 147732-56-7.

Chemical & Physical Characteristics

• Common Name: Pal-GHK / Palmitoyl Tripeptide-1
• Sequence: Palmitoyl-Gly-His-Lys
• CAS Number: 147732-56-7
• Molecular Formula: C₃₀H₅₄N₆O₅
• Molecular Weight: ~578.79 g/mol
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in DMSO and ethanol; limited aqueous solubility due to lipid chain
• Storage Temperature: −20°C (long-term); +4°C (short-term, desiccated)
• Application Format: Topical research formulations

Purity & Analytical Verification (HPLC & MS)

Every batch of Pal-GHK supplied by The Peptide Store is manufactured to a minimum purity of ≥98%, verified by reverse-phase high-performance liquid chromatography (RP-HPLC). Mass spectrometry (MS) confirmation is performed to validate the molecular identity and integrity of each production lot. Researchers can be confident that the compound they receive meets rigorous analytical benchmarks consistent with high-grade laboratory reagent standards. Certificate of Analysis (CoA) documentation is available upon request and may be provided with shipment.

Quality Control & Lyophilization Integrity

Pal-GHK is produced under controlled synthesis conditions and lyophilized to remove residual solvents and moisture, resulting in a stable, free-flowing powder suitable for long-term storage and research formulation. Lyophilization ensures batch-to-batch consistency in mass, appearance, and reconstitution behavior. Each unit undergoes quality control review prior to dispatch to confirm that physical and chemical integrity standards are maintained throughout the supply chain.

Safety, Handling & Laboratory Precautions

As with all research-grade peptides and chemical reagents, Pal-GHK should be handled in accordance with standard laboratory safety protocols. Researchers should wear appropriate personal protective equipment (PPE), including gloves, lab coat, and eye protection, when handling this compound. The material should be kept away from heat, open flame, and incompatible substances. Refer to the Safety Data Sheet (SDS) for complete hazard classification and first-aid procedures. This compound is strictly for in vitro and qualified research laboratory use.

Reconstitution, Packaging & Storage

Pal-GHK is supplied as a lyophilized powder in sealed, research-grade packaging designed to protect compound integrity during transit and storage. Due to its palmitoyl conjugation, the peptide exhibits reduced aqueous solubility; researchers typically prepare working solutions using DMSO, ethanol, or appropriate co-solvent systems suited to their specific experimental protocols. Storage at −20°C under desiccated conditions is recommended for long-term preservation. Avoid repeated freeze-thaw cycles to maintain compound stability. All reconstitution procedures should be conducted within a qualified research laboratory setting.

Intended Research Use & Market Positioning

Pal-GHK is widely referenced in peer-reviewed literature focused on peptide–lipid interactions, dermal matrix research, and topical delivery system studies. It is positioned as a premium topical research peptide for investigators studying biomimetic lipopeptide behavior, skin barrier permeation models, and extracellular matrix modulation in vitro. The Peptide Store offers Pal-GHK at a competitive best price for researchers seeking reliable, analytically verified material without compromise on quality.

Ordering, Availability & Fulfillment

Pal-GHK (Palmitoyl Tripeptide-1) is available for sale online through The Peptide Store with streamlined ordering and prompt dispatch. Researchers can order now with confidence, knowing that each unit is batch-tested, CoA-backed, and packaged for safe delivery. We support research institutions, independent laboratories, and academic procurement teams with reliable stock availability and responsive fulfillment logistics.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Pal-GHK (Palmitoyl Tripeptide-1) is sold exclusively as a laboratory research reagent. The Peptide Store makes no claims regarding therapeutic efficacy, safety for human administration, or suitability for any use beyond qualified scientific research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the acquisition, handling, and use of research peptides and chemical compounds.