Syn-AKE 200mg (Topical)

Syn-AKE 200mg (Topical) is a synthetic tripeptide derivative engineered to replicate the neuromuscular-modulating activity of Waglerin-1, a bioactive peptide isolated from the venom of the Temple Viper (Tropidolaemus wagleri). Available at ≥98% purity, this topical-grade research compound is supplied exclusively for in vitro and laboratory research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Syn-AKE — formally identified as Dipeptide Diaminobutyroyl Benzylamide Diacetate — is a reversible antagonist of the muscular nicotinic acetylcholine receptor (mnAChR). Its molecular design closely mirrors the active sequence of Waglerin-1, enabling researchers to study synaptic transmission inhibition and neuromuscular signaling pathways within controlled laboratory environments. The Peptide Store supplies this compound in a 200mg topical-grade presentation, formulated to support advanced dermatological tissue model research and receptor-binding studies.

Peptide Structure & Amino Acid Sequence

Syn-AKE is a tripeptide analogue structured as a diaminobutyroyl benzylamide diacetate salt. Its compact three-residue configuration is specifically engineered to achieve selective binding at the epsilon (ε) subunit of the nicotinic acetylcholine receptor. This targeted architecture allows for precise modulation of postsynaptic membrane activity, making it a highly reproducible tool for neuromuscular research without the variability inherent in crude biological venoms.

Chemical & Physical Characteristics

• Chemical Name: Dipeptide Diaminobutyroyl Benzylamide Diacetate
• Molecular Formula: C₁₄H₂₁N₅O₂ · 2(C₂H₄O₂)
• Molecular Weight: Approximately 441.5 g/mol
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and standard topical carrier solutions
• CAS Number: 823202-99-9

These physical characteristics make Syn-AKE particularly well-suited for incorporation into topical research formulations and ex vivo tissue model systems.

Purity & Analytical Verification (HPLC & MS)

Every batch of Syn-AKE 200mg supplied by The Peptide Store is validated to a minimum purity of ≥98% using high-performance liquid chromatography (HPLC). Mass spectrometry (MS) analysis is additionally applied to confirm molecular identity and structural integrity. These dual analytical verification methods ensure that researchers receive a compound of consistent, publication-grade quality suitable for reproducible experimental outcomes.

Quality Control & Lyophilization Integrity

Syn-AKE 200mg is produced under stringent quality control protocols. The lyophilization process removes residual moisture while preserving the peptide’s structural conformation and receptor-binding fidelity. Each unit undergoes batch-level testing prior to release, with documentation available to support research reproducibility. The Peptide Store’s quality assurance pipeline ensures that every order meets the highest standards expected by professional research teams.

Safety, Handling & Laboratory Precautions

As with all research-grade peptides, standard laboratory safety protocols must be observed when handling Syn-AKE 200mg. Researchers should wear appropriate personal protective equipment (PPE), including gloves, lab coat, and eye protection. This compound should be handled exclusively by trained laboratory personnel in a controlled research setting. It must not be administered to humans or animals under any circumstances.

• Store away from direct light and heat sources
• Keep out of reach of non-laboratory personnel
• Dispose of unused material in accordance with institutional waste disposal guidelines

Reconstitution, Packaging & Storage

Syn-AKE 200mg is delivered as a lyophilized powder in a sealed, research-grade vial. For optimal stability, the compound should be stored at −20°C upon receipt and kept away from repeated freeze-thaw cycles. Reconstitution should be performed using appropriate research-grade solvents or carrier solutions as determined by the specific experimental protocol. Reconstituted solutions should be aliquoted and stored at −80°C where extended stability is required. This product is not supplied with reconstitution instructions for injection or consumptive use.

Intended Research Use & Market Positioning

Syn-AKE 200mg is positioned as a premium topical-grade research peptide for scientists investigating nicotinic acetylcholine receptor pharmacology, neuromuscular junction signaling, and dermatological tissue model responses. Its well-defined mechanism of reversible mnAChR antagonism makes it a preferred compound for researchers seeking a reproducible, synthetic alternative to crude venom-derived fractions. The Peptide Store offers this compound at a competitive best price for research institutions, academic laboratories, and independent scientists.

Ordering, Availability & Fulfillment

Syn-AKE 200mg (Topical) is available to buy online now through The Peptide Store. Orders are processed promptly, with fast fulfillment and secure packaging to preserve compound integrity during transit. Whether you are looking to order now for an ongoing study or sourcing Syn-AKE for sale as part of a new research initiative, The Peptide Store provides a reliable, compliant supply channel with transparent batch documentation available upon request.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Syn-AKE 200mg is supplied strictly as a laboratory research reagent. The Peptide Store makes no claims regarding therapeutic efficacy, safety for consumption, or suitability for any application outside of controlled scientific research. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international regulations governing the acquisition, handling, and use of research peptides. This product must not be used in any manner inconsistent with its research-only designation.