Melanotan 2 (MT2) (3mg x 10 Vials = 30mg)

The Peptide Store is proud to offer Melanotan 2 (MT-II), a premium-grade synthetic cyclic heptapeptide supplied as a convenient multi-vial research pack at ≥98% purity, verified by HPLC and mass spectrometry. This formulation is engineered exclusively for advanced in vitro and in vivo laboratory research applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

Melanotan 2 (MT-II) is one of the most extensively studied synthetic melanocortin receptor agonists in modern peptide research. Modeled after the endogenous tridecapeptide alpha-melanocyte-stimulating hormone (α-MSH), MT-II has become an indispensable tool for researchers investigating G-protein coupled receptor (GPCR) signaling, neuroendocrine feedback dynamics, and multi-receptor melanocortin pathway interactions. The Peptide Store supplies this compound in a multi-vial configuration, providing investigators with the flexibility and consistency demanded by rigorous experimental protocols. Available to buy online with fast fulfillment and competitive pricing, this research-grade formulation is positioned as a leading choice for laboratories worldwide.

Peptide Structure & Amino Acid Sequence

Melanotan 2 is a synthetic cyclic heptapeptide analog defined by the modified sequence Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂. This structure incorporates a central lactam ring closure between the Asp and Lys residues, a design feature that confers exceptional conformational rigidity and markedly superior resistance to enzymatic degradation when compared to native linear α-MSH fragments. The incorporation of D-phenylalanine at position 4 and norleucine (Nle) at the N-terminus further enhances receptor binding affinity and metabolic stability. These structural refinements make MT-II a nonselective melanocortin receptor agonist with documented binding activity across MC1R through MC5R subtypes, making it a highly versatile ligand for multi-receptor pharmacological studies.

Chemical & Physical Characteristics

• Chemical Name: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
• CAS Number: 121062-08-6
• Molecular Formula: C₅₀H₆₉N₁₅O₉
• Molecular Weight: 1024.18 g/mol
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and standard laboratory solvents
• Peptide Class: Synthetic cyclic heptapeptide; nonselective melanocortin receptor agonist
• Receptor Targets: MC1R, MC2R, MC3R, MC4R, MC5R

Purity & Analytical Verification (HPLC & MS)

Every batch of Melanotan 2 supplied by The Peptide Store undergoes rigorous analytical verification to confirm a minimum purity of ≥98%. High-performance liquid chromatography (HPLC) is employed to resolve and quantify peptide content with high precision, while mass spectrometry (MS) confirms correct molecular identity and rules out synthetic by-products or degradation fragments. These dual-method quality assurance protocols ensure that researchers receive a compound of the highest analytical integrity, suitable for reproducible, publication-quality experimental data.

Quality Control & Lyophilization Integrity

Melanotan 2 is supplied in lyophilized (freeze-dried) powder form, a preservation method that maximizes long-term stability and protects the peptide’s structural and biological integrity during storage and transit. Each of the ten individual glass vials is sealed under inert conditions to prevent moisture ingress and oxidative degradation. Batch-specific certificates of analysis (CoA) are available upon request, providing full traceability from synthesis through to final quality release. The Peptide Store’s commitment to lyophilization integrity ensures that each vial delivers consistent, reliable performance across all research applications.

Safety, Handling & Laboratory Precautions

Melanotan 2 is supplied exclusively for qualified laboratory research personnel. Appropriate personal protective equipment (PPE), including gloves, lab coat, and eye protection, should be worn at all times when handling this compound. Standard laboratory biosafety protocols must be observed. This peptide is not approved for administration to humans or animals and must be handled in accordance with applicable institutional and regulatory guidelines governing research-grade chemical substances.

Reconstitution, Packaging & Storage

Each vial contains lyophilized MT-II powder suitable for reconstitution using standard laboratory-grade aqueous buffers or solvents appropriate to the specific research application. Reconstitution should be performed under sterile laboratory conditions by qualified research personnel. For long-term stability, lyophilized vials should be stored at −20°C, protected from light and moisture. Once reconstituted, solutions should be aliquoted and stored at −80°C or used promptly to minimize degradation. The multi-vial format supports efficient aliquoting strategies and reduces freeze-thaw cycling across extended research programs.

Intended Research Use & Market Positioning

Melanotan 2 is positioned as a premier research tool for academic institutions, pharmaceutical research organizations, and independent laboratories engaged in melanocortin biology, GPCR pharmacology, neuroendocrine signaling, and pigmentation pathway research. The multi-vial format offered by The Peptide Store provides an economical, high-volume solution for sustained research programs requiring consistent compound access. Researchers looking to buy Melanotan 2 online will find this formulation represents outstanding value, combining analytical rigor with practical laboratory convenience.

Ordering, Availability & Fulfillment

The Peptide Store offers Melanotan 2 for sale with streamlined online ordering, competitive best-price guarantees, and prompt global fulfillment. Orders are processed efficiently and dispatched with appropriate cold-chain packaging to preserve lyophilized integrity during transit. Our dedicated support team is available to assist with documentation requests, bulk ordering inquiries, and certificate of analysis requirements. Order now to secure your supply and maintain uninterrupted research continuity.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Melanotan 2 (MT-II) is sold exclusively as a laboratory research reagent. The Peptide Store makes no representations regarding the safety, efficacy, or suitability of this compound for any use outside of controlled laboratory research settings. Purchasers are solely responsible for ensuring compliance with all applicable local, national, and international laws and regulations governing the procurement, storage, and use of research peptides. This product is not a drug, pharmaceutical, dietary supplement, or consumer product of any kind.