PT-141 (3mg x 10 Vials = 30mg)

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide melanocortin receptor agonist available from The Peptide Store at ≥98% purity, supplied as a multi-vial research kit for advanced laboratory investigation. Each vial is individually lyophilized and vacuum-sealed to ensure chemical integrity across extended multi-subject protocols. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

PT-141, scientifically designated as Bremelanotide, is a purified cyclic heptapeptide structurally derived from alpha-melanocyte-stimulating hormone (α-MSH) and identified as a metabolite analog of Melanotan II. Unlike its precursor, PT-141 lacks the C-terminal amide group, a structural modification that meaningfully alters its receptor affinity profile and reduces peripheral melanogenesis signaling. This compound has attracted significant interest in preclinical research settings focused on central nervous system signaling, autonomic pathway modulation, and microvascular dynamics. The Peptide Store supplies PT-141 exclusively for qualified laboratory and research applications.

Peptide Structure & Amino Acid Sequence

PT-141 is a cyclic heptapeptide with the amino acid sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Its cyclic backbone confers enhanced conformational rigidity compared to linear peptide analogs, contributing to its binding selectivity at melanocortin receptor subtypes MC1R, MC3R, MC4R, and MC5R. The absence of the C-terminal amide distinguishes PT-141 from Melanotan II and is associated with a modified pharmacodynamic profile relevant to central rather than peripheral receptor engagement — a distinction of particular interest in neuroendocrine and autonomic research contexts.

Chemical & Physical Characteristics

• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Molecular Weight: 1025.17 g/mol
• CAS Number: 189691-06-3
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and standard laboratory solvents
• Storage Stability: Stable under recommended cold-chain and lyophilized conditions

The cyclic structure of PT-141 provides notable resistance to enzymatic degradation compared to linear peptide counterparts, making it a technically favorable compound for sustained in vitro and ex vivo experimental protocols.

Purity & Analytical Verification (HPLC & MS)

Every batch of PT-141 supplied by The Peptide Store undergoes rigorous analytical verification to confirm a minimum purity of ≥98%. High-Performance Liquid Chromatography (HPLC) is employed to quantify peptide purity and identify any trace impurities or synthesis byproducts. Mass Spectrometry (MS) confirms molecular identity and structural integrity, ensuring that the compound delivered to researchers is analytically consistent with published reference standards. Certificate of Analysis (CoA) documentation is available upon request for full batch traceability.

Quality Control & Lyophilization Integrity

Each individual 3mg vial in this research kit is independently lyophilized under controlled freeze-drying conditions and vacuum-sealed to eliminate moisture ingress and oxidative degradation. This vial-by-vial preparation methodology ensures precise quantity allocation across multi-subject or longitudinal research designs, eliminates cross-contamination risk between experimental sessions, and preserves compound stability throughout the product’s shelf life. The Peptide Store’s quality control pipeline applies standardized batch release criteria to every product prior to fulfillment.

Safety, Handling & Laboratory Precautions

PT-141 is intended exclusively for use by trained laboratory professionals operating within appropriately equipped research facilities. Standard laboratory personal protective equipment (PPE) — including gloves, eye protection, and appropriate lab attire — should be worn when handling lyophilized peptide materials. This compound is not approved for administration to humans or animals and must not be used in any clinical, therapeutic, or consumptive context. Researchers should adhere to all applicable institutional biosafety protocols and local regulatory guidelines governing peptide research materials.

Reconstitution, Packaging & Storage

PT-141 is supplied in lyophilized powder form across 10 individually sealed vials. For laboratory reconstitution, researchers should follow validated protocols using appropriate sterile aqueous buffers as required by their specific experimental design. Lyophilized vials should be stored at −20°C for long-term preservation, with short-term working stocks maintained at 4°C away from light and humidity. Avoid repeated freeze-thaw cycles to maintain compound integrity. Reconstituted solutions should be used promptly in accordance with standard laboratory best practices.

Intended Research Use & Market Positioning

PT-141 Bremelanotide is positioned as a premium research-grade melanocortin receptor agonist for investigators studying central melanocortin system signaling, autonomic nervous system modulation, and microvascular regulatory mechanisms. It is widely referenced in preclinical literature exploring neuroendocrine axes and receptor subtype selectivity. The Peptide Store offers this compound at a competitive best price with consistent batch quality, making it a preferred choice for researchers seeking reliable, analytically verified peptide materials for ongoing protocols.

Ordering, Availability & Fulfillment

PT-141 (Bremelanotide) 30mg is available to order now directly through The Peptide Store’s secure online platform. This research peptide is in stock and ready for prompt dispatch with tracked shipping options available. Researchers and laboratory procurement teams can buy online with confidence, supported by transparent CoA documentation, responsive customer service, and competitive pricing. Bulk inquiry options are available for institutions requiring larger quantities.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. PT-141 (Bremelanotide) is sold exclusively as a laboratory research reagent. The Peptide Store makes no representations regarding the suitability of this compound for any application beyond qualified scientific research. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international regulations governing the acquisition, storage, and use of research peptides. This product has not been evaluated or approved by any regulatory authority for therapeutic or consumer use.