PT-141 10mg

PT-141 (Bremelanotide) 10mg is a high-purity synthetic cyclic heptapeptide analog of endogenous alpha-melanocyte-stimulating hormone (α-MSH), available from The Peptide Store at ≥98% purity. Engineered for advanced laboratory research, this lyophilized compound is designed to support multi-dose experimental protocols, automated assay configurations, and long-term neuroendocrinology studies. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

PT-141, also known by its investigational designation Bremelanotide, is a neuroactive cyclic heptapeptide structurally derived as a purified metabolite of Melanotan II. Unlike its precursor, PT-141 lacks the C-terminal amide group — a critical structural modification that meaningfully alters its melanocortin receptor affinity profile and substantially reduces local melanogenesis signaling. This renders PT-141 a highly selective research tool for studies focused on central nervous system (CNS) signaling, neurogenic autonomic pathways, and microvascular modulation. Available for sale at The Peptide Store, this 10mg configuration represents an advanced baseline concentration suited for comprehensive, multi-phase laboratory investigations.

Peptide Structure & Amino Acid Sequence

PT-141 is a cyclic heptapeptide with the amino acid sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH. Its cyclic backbone confers enhanced conformational rigidity compared to linear peptide analogs, contributing to its documented receptor selectivity and relative metabolic stability in aqueous research environments. The substitution of D-phenylalanine at position 4 and the incorporation of norleucine (Nle) at position 1 are key structural features that distinguish PT-141 from native α-MSH and define its unique pharmacological research profile. These structural attributes make it a valuable compound for investigations into melanocortin receptor subtypes MC3R and MC4R.

Chemical & Physical Characteristics

• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Molecular Weight: Approximately 1025.18 g/mol
• CAS Number: 189691-06-3
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in aqueous buffers and standard laboratory solvents
• Peptide Classification: Synthetic cyclic heptapeptide; melanocortin receptor agonist analog
• Storage Stability: Lyophilized form provides enhanced long-term stability under recommended conditions

Purity & Analytical Verification (HPLC & MS)

Every batch of PT-141 10mg supplied by The Peptide Store undergoes rigorous analytical verification to confirm ≥98% purity. High-Performance Liquid Chromatography (HPLC) is employed to quantify peptide content and identify any residual impurities, while Mass Spectrometry (MS) confirms molecular identity and structural integrity. These dual-verification methods ensure that each unit delivered to the research laboratory meets the exacting standards required for reproducible, publication-quality experimental results. Certificates of Analysis (CoA) are available upon request, providing full transparency into batch-specific purity data.

Quality Control & Lyophilization Integrity

PT-141 10mg is produced under stringent quality control protocols throughout the synthesis, purification, and lyophilization stages. The lyophilization process removes residual moisture to below critical thresholds, preserving peptide integrity and preventing degradation during transit and storage. Each unit is sealed under inert conditions to protect against oxidative and hydrolytic degradation. The Peptide Store’s quality assurance framework ensures batch-to-batch consistency, supporting the reproducibility demands of long-term and multi-arm research studies.

Safety, Handling & Laboratory Precautions

PT-141 10mg is intended exclusively for qualified researchers and licensed laboratory professionals operating within appropriately equipped facilities. Standard laboratory personal protective equipment (PPE) — including nitrile gloves, safety eyewear, and a laboratory coat — should be worn when handling this compound. Researchers should consult the relevant Safety Data Sheet (SDS) prior to use. This compound is not approved for administration to humans or animals, and must not be used in any clinical, diagnostic, or therapeutic context. All handling, storage, and disposal must comply with applicable institutional and regulatory guidelines.

Reconstitution, Packaging & Storage

PT-141 10mg is supplied as a sterile lyophilized powder in a sealed, laboratory-grade vial optimized for research use. Reconstitution should be performed using appropriate laboratory-grade solvents in accordance with the researcher’s experimental protocol. The lyophilized product should be stored at −20°C for long-term preservation, with short-term storage permissible at 4°C in a dry, light-protected environment. Once reconstituted, solutions should be handled and stored according to standard peptide research best practices. Repeated freeze-thaw cycles should be avoided to maintain compound integrity.

Intended Research Use & Market Positioning

PT-141 10mg is positioned as a premium research-grade tool for neuroendocrinology, autonomic neuroscience, and receptor pharmacology laboratories. Its well-characterized melanocortin receptor agonism profile — particularly at MC3R and MC4R subtypes — makes it a sought-after compound for investigations into CNS signaling cascades, neurogenic autonomic regulation, and microvascular biology. Researchers looking to buy PT-141 online will find The Peptide Store’s 10mg offering ideally suited for multi-dose experimental designs, automated liquid-handling assay setups, and extended longitudinal studies requiring stable baseline compound availability.

Ordering, Availability & Fulfillment

PT-141 10mg is available for sale now through The Peptide Store, with secure online ordering and prompt fulfillment. We offer competitive best-price positioning on all research peptides, with fast dispatch and discreet, research-compliant packaging. Orders are processed efficiently to minimize laboratory downtime. For bulk purchasing inquiries, institutional procurement, or CoA requests, contact The Peptide Store’s dedicated research support team. Order now and benefit from our commitment to quality, compliance, and customer service excellence.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. PT-141 10mg is sold exclusively as a laboratory research compound. It has not been evaluated or approved by the FDA or any equivalent regulatory authority for use in humans or animals. The purchaser assumes full responsibility for compliance with all applicable local, national, and international laws and regulations governing the acquisition, handling, storage, and use of research peptides. The Peptide Store makes no therapeutic, medical, or health-related claims regarding this product.